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Holger Thiele Selected Research

Reperfusion Injury

12/2023Reperfusion Injury: How Can We Reduce It by Pre-, Per-, and Postconditioning.
11/2023Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection.
3/2020Impact of Morphine Treatment on Infarct Size and Reperfusion Injury in Acute Reperfused ST-Elevation Myocardial Infarction.
10/2019Combined Intrahospital Remote Ischemic Perconditioning and Postconditioning Improves Clinical Outcome in ST-Elevation Myocardial Infarction.
11/2016Antecedent hypertension and myocardial injury in patients with reperfused ST-elevation myocardial infarction.
1/2016Smoke over myocardial infarction: cigarettes and reperfusion injury.
4/2013Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial.
5/2010Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-N-ACC (Prospective, Single-Blind, Placebo-Controlled, Randomized Leipzig Immediate PercutaneouS Coronary Intervention Acute Myocardial Infarction N-ACC) Trial.
5/2010Endothelin-1 release in acute myocardial infarction as a predictor of long-term prognosis and no-reflow assessed by contrast-enhanced magnetic resonance imaging.

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Holger Thiele Research Topics

Disease

126Myocardial Infarction
05/2024 - 07/2003
114Cardiogenic Shock
05/2024 - 09/2004
103ST Elevation Myocardial Infarction
02/2024 - 11/2006
81Infarction (Infarctions)
05/2024 - 10/2005
72Heart Failure
05/2024 - 10/2003
57Shock
01/2024 - 09/2011
47Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 07/2008
35Thrombosis (Thrombus)
12/2023 - 01/2003
30Hemorrhage
03/2024 - 04/2014
30Stroke (Strokes)
02/2024 - 10/2008
25Atrial Fibrillation
04/2024 - 10/2016
22Coronary Artery Disease (Coronary Atherosclerosis)
12/2023 - 07/2003
18Aortic Valve Stenosis (Aortic Stenosis)
04/2024 - 03/2016
16Acute Coronary Syndrome
01/2024 - 03/2010
15Non-ST Elevated Myocardial Infarction
02/2024 - 08/2012
14Hypertension (High Blood Pressure)
01/2024 - 06/2015
13Pathologic Constriction (Stenosis)
12/2020 - 01/2003
12Diabetes Mellitus
06/2022 - 07/2003
10Takotsubo Cardiomyopathy
05/2024 - 06/2009
10Mitral Valve Insufficiency (Mitral Regurgitation)
02/2024 - 01/2018
10Heart Arrest (Cardiac Arrest)
12/2023 - 07/2011
9Reperfusion Injury
12/2023 - 05/2010
8Cardiomyopathies (Cardiomyopathy)
04/2024 - 12/2016
8Acute Kidney Injury (Acute Renal Failure)
04/2024 - 01/2018
8Neoplasms (Cancer)
04/2024 - 02/2015
8Inflammation (Inflammations)
11/2022 - 12/2016
8Epilepsy (Aura)
01/2018 - 01/2013
6Endocarditis
08/2023 - 01/2018
5Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve)
03/2024 - 01/2020
5Disease Progression
09/2023 - 04/2014
5Renal Insufficiency (Renal Failure)
01/2023 - 02/2016
5Intellectual Disability (Idiocy)
01/2022 - 11/2012
4Ovarian Neoplasms (Ovarian Cancer)
04/2024 - 01/2019
4Chest Pain (Chest Pains)
01/2023 - 06/2009
4Hypothermia
12/2022 - 08/2013
4Microcephaly
01/2022 - 11/2012
4Ataxia (Dyssynergia)
12/2021 - 07/2013
4Obesity
10/2021 - 01/2013
4Ciliopathies
11/2019 - 10/2014
4Hearing Loss (Hearing Impairment)
02/2016 - 05/2002
3Lacerations
03/2024 - 10/2020
3Nervous System Diseases (Neurological Disorders)
02/2024 - 11/2012
3Sepsis (Septicemia)
01/2024 - 08/2015
3Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2024 - 08/2013
3Ventricular Fibrillation
01/2024 - 01/2020
3Myocardial Ischemia (Ischemic Heart Diseases)
12/2023 - 10/2005

Drug/Important Bio-Agent (IBA)

41omega-Chloroacetophenone (Mace)IBA
01/2024 - 04/2005
31Biomarkers (Surrogate Marker)IBA
05/2024 - 04/2006
18Abciximab (ReoPro)FDA Link
08/2021 - 11/2006
14Proteins (Proteins, Gene)FDA Link
11/2023 - 09/2008
9Lactic Acid (Lactate)FDA LinkGeneric
11/2023 - 08/2014
9TroponinIBA
07/2023 - 09/2015
7DNA (Deoxyribonucleic Acid)IBA
04/2024 - 10/2014
7EnzymesIBA
09/2023 - 06/2009
7GadoliniumIBA
08/2021 - 09/2011
6CatecholaminesIBA
01/2024 - 09/2010
6Prasugrel HydrochlorideFDA Link
09/2021 - 01/2015
6TicagrelorIBA
09/2021 - 12/2016
6Glycoproteins (Glycoprotein)IBA
01/2019 - 07/2009
6Sirolimus (Rapamycin)FDA Link
01/2015 - 06/2009
52'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
01/2024 - 01/2021
5Arginine (L-Arginine)FDA Link
09/2023 - 01/2020
5CytokinesIBA
11/2022 - 10/2003
5Troponin T (Troponin T1)IBA
09/2021 - 04/2014
5Clopidogrel (Plavix)FDA Link
09/2021 - 06/2014
5Creatine Kinase (Creatine Phosphokinase)IBA
01/2021 - 11/2009
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2023 - 01/2011
4NucleotidesIBA
01/2023 - 02/2016
4Protein Isoforms (Isoforms)IBA
06/2022 - 02/2016
4Brain Natriuretic Peptide (Natrecor)FDA Link
01/2021 - 01/2018
4Morphine (MS Contin)FDA LinkGeneric
01/2021 - 09/2015
4Paclitaxel (Taxol)FDA LinkGeneric
01/2020 - 04/2011
4Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2020 - 01/2003
4Glucose (Dextrose)FDA LinkGeneric
01/2018 - 11/2012
4CreatinineIBA
04/2017 - 05/2010
3Galectin 3 (LGALS3)IBA
05/2024 - 03/2017
3Indicators and Reagents (Reagents)IBA
02/2024 - 11/2015
3EverolimusFDA Link
01/2024 - 01/2021

Therapy/Procedure

147Percutaneous Coronary Intervention
05/2024 - 01/2003
85Therapeutics
04/2024 - 01/2003
34Transcatheter Aortic Valve Replacement
04/2024 - 01/2018
28Stents
01/2024 - 01/2003
26Extracorporeal Membrane Oxygenation
05/2024 - 03/2010
20Counterpulsation (External Counterpulsation)
01/2023 - 07/2005
14Coronary Artery Bypass (Coronary Artery Bypass Surgery)
11/2023 - 07/2003
12Renal Replacement Therapy (Therapies, Renal Replacement)
12/2023 - 02/2016
11Critical Care (Surgical Intensive Care)
07/2023 - 08/2015
10Patient Readmission
04/2024 - 08/2012
8Length of Stay
02/2024 - 09/2004
8Heart-Assist Devices
07/2021 - 07/2005
7Catheters
10/2022 - 06/2015
6Resuscitation
11/2023 - 05/2015
5Cardiopulmonary Resuscitation (CPR)
01/2024 - 05/2016
5Denervation
10/2023 - 01/2019
5Bioprosthesis
01/2023 - 11/2019
5Sympathectomy (Sympathectomies)
01/2021 - 06/2015
5Thrombectomy
10/2020 - 04/2013
4Drug Therapy (Chemotherapy)
04/2024 - 08/2019
4Prostheses and Implants (Prosthesis)
02/2024 - 01/2020
4Drug-Eluting Stents
08/2017 - 01/2010